The Substance

Have you ever dreamt of a better version of yourself?

Duration: 141 min
Release date: 2024-09-07
IMDB

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

Drama Horror Science Fiction

The Substance

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Casting arrow_drop_down

Demi Moore
Demi Moore
as Elisabeth
Margaret Qualley
Margaret Qualley
as Sue
Dennis Quaid
Dennis Quaid
as Harvey
Edward Hamilton-Clark
Edward Hamilton-Clark
as Fred
Gore Abrams
Gore Abrams
as Oliver
Oscar Lesage
Oscar Lesage
as Troy
Christian Erickson
Christian Erickson
as Man at Diner
Robin Greer
Robin Greer
as Male Nurse
Tom Morton
Tom Morton
as Doctor
Hugo Diego Garcia
Hugo Diego Garcia
as Diego - Boyfriend
Daniel Knight
Daniel Knight
as Casting Director
Jonathon Carley
Jonathon Carley
as Assistant Casting Director
Jiselle Henderkott
Jiselle Henderkott
as Girl Auditioning / New Year's Eve Show Dancer
Akil Wingate
Akil Wingate
as TV Host
Vincent Colombe
Vincent Colombe
as Man in Suit #1 - Harvey's Office
Billy Bentley
Billy Bentley
as Man in Suit #2
Lennard Ridsdale
Lennard Ridsdale
as Man in Suit #3
Jordan Ford Silver
Jordan Ford Silver
as Assistant Director - Pump It Up Show
Oscar Salem
Oscar Salem
as 2nd Assistant Director - Pump It Up Show
Viviane Bossina
Viviane Bossina
as Sue's Assistant
Matthew Luret
Matthew Luret
as Floor Runner
Jana Bittnerová
Jana Bittnerová
as Maria
Olivier Raynal
Olivier Raynal
as Alan - 2nd Agent
Tiffany Hofstetter
Tiffany Hofstetter
as Stylist
Nicolas Royer
Nicolas Royer
as Guy in the Elevator
Nathan Rippy
Nathan Rippy
as Assistant Director - New Year's Eve Show
Manon Arizmendi
Manon Arizmendi
as Little Girl - New Year's Eve Show
Virginie Kotlinski
Virginie Kotlinski
as Mother - New Year's Eve Show
Brett Gillen
Brett Gillen
as Director of Photography - New Year's Eve Show
Charlotte Marquardt
Charlotte Marquardt
as Screaming Woman
Léa Hengl
Léa Hengl
as Screaming Woman
Gaëlle Raymond
Gaëlle Raymond
as Screaming Woman
Claire Lemaire
Claire Lemaire
as Screaming Woman
Lila Boughoufala
Lila Boughoufala
as Screaming Woman
Aurélien Lorgnier
Aurélien Lorgnier
as Screaming Man
Ivan Sellier
Ivan Sellier
as Screaming Man
Philip Schurer
Philip Schurer
as Screaming Man
Christian Bourmier
Christian Bourmier
as Shareholder
Martin Graham
Martin Graham
as Shareholder
Christian Bordeleau
Christian Bordeleau
as Shareholder
Patrick Hamel
Patrick Hamel
as Shareholder
Didier Dhondt
Didier Dhondt
as Shareholder
Jacques-Yves Dorges
Jacques-Yves Dorges
as Shareholder
Jean-Claude Matthey
Jean-Claude Matthey
as Shareholder
Olivier Jarcin
Olivier Jarcin
as Shareholder
Jean-Luc Magneron
Jean-Luc Magneron
as Shareholder
Charlotte Murray
Charlotte Murray
as Allison - Diner Waitress
Aaron Kahn
Aaron Kahn
as Greeting Person
Gabriela Arnon
Gabriela Arnon
as Greeting Person
Nancy Josephson Lahoussine
Nancy Josephson Lahoussine
as Greeting Person
Andrew Eldridge
Andrew Eldridge
as Greeting Person
Denise Powers
Denise Powers
as Greeting Person
Bryan Jones
Bryan Jones
as Greeting Person
Adam Carage
Adam Carage
as Happy Birthday Person
Maria McClurg
Maria McClurg
as Happy Birthday Person
Andrew Desmond
Andrew Desmond
as Happy Birthday Person
Rebecca Lafont
Rebecca Lafont
as Happy Birthday Person
Laura Puech
Laura Puech
as Isabella
Ryan Chidester
Ryan Chidester
as Stagehand
Cécile Vogt
Cécile Vogt
as Elisabeth (Young) - Walk of Fame / Pump It Up Show Dancer
Yannick Guérin
Yannick Guérin
as Clumsy Burger Guy - Walk of Fame
Jean Miel
Jean Miel
as Worker Walk of Fame
Paul Descoings
Paul Descoings
as Worker Walk of Fame
Benoit Lévêque
Benoit Lévêque
as Worker Walk of Fame
Arthur Molinet
Arthur Molinet
as Cocktail Bartender
Manon Sachot
Manon Sachot
as Cocktail Lounge Couple
Bastien Jorelle
Bastien Jorelle
as Cocktail Lounge Couple
Kelly Hoarau
Kelly Hoarau
as Female Assistant - Towel
Michel Juskiewicz
Michel Juskiewicz
as George - Harvey's Friend
Louise Greggory
Louise Greggory
as Restaurant Waitress
Christophe Sartirano
Christophe Sartirano
as Guy Looking at Sue
Florent Torres
Florent Torres
as Guy Looking at Sue
Romain Caldeira
Romain Caldeira
as Billboard Technician
Barthelemy Thomas
Barthelemy Thomas
as Billboard Technician
Axel Baille
Axel Baille
as Photographer
Ashley Lambert
Ashley Lambert
as Additional Voices (voice)
Ranjani Brow
Ranjani Brow
as Additional Voices (voice)
Chase Fein
Chase Fein
as Additional Voices (voice)
Shane Sweet
Shane Sweet
as Additional Voices (voice)
William Calvert
William Calvert
as Additional Voices (voice)
Michael Corbett
Michael Corbett
as Additional Voices (voice)
Stephen Apostolina
Stephen Apostolina
as Additional Voices (voice)
Yann Bean
Yann Bean
as The Substance (voice)
Audjyan Alcide
Audjyan Alcide
as Pump It Up Show Dancer
Jonathan Jenvrin
Jonathan Jenvrin
as Pump It Up Show Dancer
Mimi Maury
Mimi Maury
as Pump It Up Show Dancer
Amelye Solange
Amelye Solange
as Pump It Up Show Dancer
Kévin Table
Kévin Table
as Pump It Up Show Dancer
Laura Boera
Laura Boera
as Sparkle Your Life Show Dancer
Cissy Duc
Cissy Duc
as Sparkle Your Life Show Dancer
Sophie Mercier
Sophie Mercier
as Sparkle Your Life Show Dancer
Marie Valton
Marie Valton
as Sparkle Your Life Show Dancer
Katrina Budzynski
Katrina Budzynski
as New Year's Eve Show Dancer
Alicia Maury
Alicia Maury
as New Year's Eve Show Dancer
Megane Adamik
Megane Adamik
as New Year's Eve Show Dancer
Annalisa Pagnotta
Annalisa Pagnotta
as New Year's Eve Show Dancer
Maelle Dantigny
Maelle Dantigny
as New Year's Eve Show Dancer
Aleksandra Kedzierska Fontaine
Aleksandra Kedzierska Fontaine
as New Year's Eve Show Dancer
Pauline Sagetat
Pauline Sagetat
as New Year's Eve Show Dancer
Agustina Fitzsimons
Agustina Fitzsimons
as New Year's Eve Show Dancer
Elena Shcheglova
Elena Shcheglova
as New Year's Eve Show Dancer
Eve Marchant
Eve Marchant
as New Year's Eve Show Dancer
Lola Donati
Lola Donati
as New Year's Eve Show Dancer
Kate Matthews
Kate Matthews
as New Year's Eve Show Dancer
Ophélie Jonard
Ophélie Jonard
as New Year's Eve Show Dancer
Pauline Richard
Pauline Richard
as New Year's Eve Show Dancer
Laureen Cappelliez
Laureen Cappelliez
as New Year's Eve Show Dancer
Daria Panchenko
Daria Panchenko
as New Year's Eve Show Dancer
Delphine Beaulieu
Delphine Beaulieu
as New Year's Eve Show Dancer
Victoria Brun
Victoria Brun
as New Year's Eve Show Dancer
Cara Chapman
Cara Chapman
as New Year's Eve Show Dancer
Katharine Matthews
Katharine Matthews
as New Year's Eve Show Dancer
Alexandra Faget
Alexandra Faget
as New Year's Eve Show Dancer
Clémence Juville
Clémence Juville
as New Year's Eve Show Dancer
Margot L'Entete
Margot L'Entete
as New Year's Eve Show Dancer
Hillary Sukhonos
Hillary Sukhonos
as New Year's Eve Show Dancer
Matthew Géczy
Matthew Géczy
as Bob Haswell (uncredited)
Namory Bakayoko
Namory Bakayoko
as Silhouette (uncredited)
Gregory Defleur
Gregory Defleur
as Happy Birthday Person (uncredited)
Coralie Fargeat
Coralie Fargeat
as (uncredited)
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Crew arrow_drop_down

Anne Juin
Anne Juin
Third Assistant Director
Erik Baiers
Erik Baiers
Executive Producer
Matthieu de la Mortière
Matthieu de la Mortière
First Assistant Director
Stanislas Reydellet
Stanislas Reydellet
Production Design
Frédérique Arguello
Frédérique Arguello
Hair Department Head
Marie Bouvet
Marie Bouvet
Stunt Double
Jérôme Gaspard
Jérôme Gaspard
Stunt Coordinator
Richard Martin
Richard Martin
Prosthetics Sculptor
Cécilia Blom
Cécilia Blom
Set Decoration
Denise Boccacci
Denise Boccacci
Prosthetic Makeup Artist
Bryan Jones
Bryan Jones
Visual Effects Supervisor
Frédéric Balmer
Frédéric Balmer
Special Effects Makeup Artist
Andrea Leanza
Andrea Leanza
Prosthetics Sculptor
Benjamin Kračun
Benjamin Kračun
Director of Photography
Jérôme Eltabet
Jérôme Eltabet
Editor
Sebastian Lochmann
Sebastian Lochmann
Concept Artist
Krystell Morantin
Krystell Morantin
Assistant Art Director
Arthur Delapierre
Arthur Delapierre
Stunts
Laure Caniaux
Laure Caniaux
First Assistant Camera
Guillemette Buffet
Guillemette Buffet
Stunt Double
Vianne Burquier
Vianne Burquier
Camera Intern
Steve de Rocco
Steve de Rocco
Camera Operator
Thomas Gros
Thomas Gros
Key Grip
William Renaud
William Renaud
Grip
Nadege Marti
Nadege Marti
Location Scout
Stephane Girondeaud
Stephane Girondeaud
Stunts
Chloè Acher
Chloè Acher
Second Assistant Camera
Marie Sergeant
Marie Sergeant
Stunts
Olivier Maurin
Olivier Maurin
Electrician
Edouard Alvernhe
Edouard Alvernhe
Electrician
Charles Droudun
Charles Droudun
Electrician
Stella Libert
Stella Libert
First Assistant Camera
Ludovic Tobaldi
Ludovic Tobaldi
Steadicam Operator
Noémie Lance
Noémie Lance
Location Manager
Fabien Pascal
Fabien Pascal
Colorist
Catherine Georges
Catherine Georges
Camera Operator
Jonas Poignant
Jonas Poignant
Third Assistant Camera
Eddy Trouillot
Eddy Trouillot
Grip
Camille Damag
Camille Damag
Costume Supervisor
Joffrey Darel
Joffrey Darel
Stunt Driver
Lucile Perez
Lucile Perez
Stunts
Marie-Sophie Daniel
Marie-Sophie Daniel
First Assistant Camera
Fabienne Menguy
Fabienne Menguy
Costume Supervisor
Ahmed Chouikhi
Ahmed Chouikhi
Stunts
Guillaume Lemerle
Guillaume Lemerle
Gaffer
Nahi Margot
Nahi Margot
Electrician
Katia Sourzac
Katia Sourzac
Location Production Assistant
Benjamin Bouygues-Faugeron
Benjamin Bouygues-Faugeron
Property Buyer
Jérémie Delaboudinière
Jérémie Delaboudinière
Stunts
Tanguy Goasguen
Tanguy Goasguen
Additional Grip
Gustin Guillaume
Gustin Guillaume
First Assistant Camera
Olivier Sargatal
Olivier Sargatal
Best Boy Electric
Céline Richard
Céline Richard
Stunts
Benjamin Colleye
Benjamin Colleye
Additional First Assistant Camera
Yann Festinger
Yann Festinger
Video Assist Operator
Benjamin Durfort
Benjamin Durfort
Assistant Editor
Baptiste Bonin
Baptiste Bonin
Props
Baptiste Herment
Baptiste Herment
Production Accountant
Baptiste Marnière
Baptiste Marnière
Digital Imaging Technician
Christine Tamalet
Christine Tamalet
Still Photographer
Coralie Fargeat
Coralie Fargeat
Director
Eric Fellner
Eric Fellner
Producer
Coralie Fargeat
Coralie Fargeat
Producer
Tim Bevan
Tim Bevan
Producer
Alexandra Loewy
Alexandra Loewy
Executive Producer
Nicolas Royer
Nicolas Royer
Executive Producer
Raffertie
Raffertie
Original Music Composer
Oriane Cattiaux
Oriane Cattiaux
Makeup Artist
Marison De
Marison De
Special Effects Makeup Artist
Sandrine Denis
Sandrine Denis
Special Effects Makeup Artist
Louis Tellier
Louis Tellier
Third Assistant Director
Honorine Sutter
Honorine Sutter
Assistant Production Manager
Jean Miel
Jean Miel
Special Effects Supervisor
Benjamin Celliez
Benjamin Celliez
Unit Production Manager
Elise Duvignau
Elise Duvignau
Props
Abraham Goldblat
Abraham Goldblat
Post Production Supervisor
Brian Kinney
Brian Kinney
Special Effects Makeup Artist
Julia Besnier
Julia Besnier
Production Accountant
Clément Audebrand
Clément Audebrand
Third Assistant Director
Stéphanie Guillon
Stéphanie Guillon
Key Makeup Artist
Caroline Vlieghe
Caroline Vlieghe
Hairstylist
Pierre-Yves Frohard
Pierre-Yves Frohard
Production Coordinator
Mateo Cejoco
Mateo Cejoco
Third Assistant Director
Barthelemy Thomas
Barthelemy Thomas
Set Dresser
Amélie Meseguer
Amélie Meseguer
Assistant Set Decoration
Mélissa Jacob
Mélissa Jacob
Additional Hairstylist
Louis Lion
Louis Lion
Digital Compositor
Olivier Afonso
Olivier Afonso
Special Effects Makeup Artist
Lucky Nguyen
Lucky Nguyen
Makeup Artist
Cynthia Scigliuto
Cynthia Scigliuto
Makeup Artist
Benoit Seiller
Benoit Seiller
Second Assistant Director
Coralie Fargeat
Coralie Fargeat
Editor
Téo L'Huillier
Téo L'Huillier
Digital Compositor
Dave Elsey
Dave Elsey
Prosthetic Supervisor
Louis Celnik
Louis Celnik
Carpenter
Lou Elsey
Lou Elsey
Prosthetic Supervisor
Bryony Rumble
Bryony Rumble
Special Effects Makeup Artist
Tiva Nagchin
Tiva Nagchin
Post Production Supervisor
Marion Didier
Marion Didier
Assistant Art Director
Guillaume Le Gouez
Guillaume Le Gouez
Visual Effects Supervisor
Christophe Arnaud
Christophe Arnaud
Additional Second Assistant Camera
Isalys Gillet
Isalys Gillet
Location Assistant
Elsa Rolland
Elsa Rolland
Assistant Property Master
Elsa Manunta
Elsa Manunta
Set Costumer
Marianne Huet
Marianne Huet
Script Supervisor
Olaf Taittinger
Olaf Taittinger
Special Effects
Louis Auger
Louis Auger
Digital Compositor
Chloé Zobel
Chloé Zobel
Property Master
Jacob Rogers
Jacob Rogers
Digital Compositor
Jacques-Emmanuel Astor
Jacques-Emmanuel Astor
Extras Casting
Jimmy Zhao
Jimmy Zhao
First Assistant Editor
Guillaume Baurez
Guillaume Baurez
Music Supervisor
Marjane Texier
Marjane Texier
Graphic Designer
Thomas Burgess
Thomas Burgess
Steadicam Operator
Christophe Riso
Christophe Riso
Assistant Location Manager
Guillaume Billy
Guillaume Billy
Camera Trainee
Raphaëlle Beck
Raphaëlle Beck
Extras Casting
Steve Sebir
Steve Sebir
Assistant Location Manager
Aurélie Boutet
Aurélie Boutet
Casting Assistant
Pierre-Olivier Persin
Pierre-Olivier Persin
Prosthetics
Pierre-Olivier Persin
Pierre-Olivier Persin
Makeup Effects Designer
Marion De Villechabrolle
Marion De Villechabrolle
Set Decoration
Valentin Féron
Valentin Féron
Editor
Stéphane Bécimol
Stéphane Bécimol
Art Direction
Emmanuelle Youchnovski
Emmanuelle Youchnovski
Costume Designer
Victor Praud
Victor Praud
Sound Re-Recording Mixer
Valérie Deloof
Valérie Deloof
Sound Designer
Judah Getz
Judah Getz
ADR Mixer
Patrick Christensen
Patrick Christensen
ADR Mixer
Emmanuelle Villard
Emmanuelle Villard
Sound Mixer
Olga Pasternak
Olga Pasternak
Supervising Dialogue Editor
Thomas Pichon
Thomas Pichon
Dialogue Editor
Stéphane Thiébaut
Stéphane Thiébaut
Sound Re-Recording Mixer
Anna Devillaire
Anna Devillaire
ADR Editor
Margaux Peyre
Margaux Peyre
Boom Operator
Antoine Swertvaegher
Antoine Swertvaegher
Foley Editor
Grégory Vincent
Grégory Vincent
Foley Artist
Claire Bernengo
Claire Bernengo
Boom Operator
Valérie Deloof
Valérie Deloof
Sound Editor
Victor Fleurant
Victor Fleurant
Sound Editor
Lucien Richardson
Lucien Richardson
Supervising Dialogue Editor
Laure Cochener
Laure Cochener
Casting
Coralie Fargeat
Coralie Fargeat
Writer
Amélie Meseguer
Amélie Meseguer
Art Direction
Arnaud Denis
Arnaud Denis
Art Direction
Gladys Garot
Gladys Garot
Art Direction
Julie Plumelle
Julie Plumelle
Art Direction
Nathalie Vaïsse
Nathalie Vaïsse
Art Direction
Pierre Procoudine-Gorsky
Pierre Procoudine-Gorsky
Visual Effects Producer
Chevin Shafaghi
Chevin Shafaghi
Visual Effects Supervisor
Serafin Bernfeld
Serafin Bernfeld
Special Effects Technician
Arthur Weiser
Arthur Weiser
Special Effects Technician
Alexandrine Mauvezin-Bosque
Alexandrine Mauvezin-Bosque
Set Dresser
Marilyne Scarselli
Marilyne Scarselli
Key Hair Stylist
Jean-Marc Benois
Jean-Marc Benois
Additional Hairstylist
Frédérique Arguello
Frédérique Arguello
Key Hair Stylist
Jérémy Lagniez
Jérémy Lagniez
Stunts
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