Pete and Debbie are both about to turn 40, their kids hate each other, both of their businesses are failing, they're on the verge of losing their house, and their relationship is threatening to fall apart.
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Paul Rudd as Pete
Leslie Mann as Debbie
John Lithgow as Oliver
Megan Fox as Desi
Maude Apatow as Sadie
Iris Apatow as Charlotte
Chris O'Dowd as Ronnie
Jason Segel as Jason
Melissa McCarthy as Catherine
Graham Parker as Graham Parker
Albert Brooks as Larry
Lena Dunham as Cat
Annie Mumolo as Barb
Robert Smigel as Barry
Charlyne Yi as Jodi
Lisa Darr as Clair
Billie Joe Armstrong as Billie Joe Armstrong
Michael Ian Black as Accountant
Wyatt Russell as Flirty Hockey Player
Tom Yi as Charlotte's Teacher
Tim Bagley as Dr. Pellegrino
Ava Sambora as Wendy
Megan Grano as School Playdate Parent
D.A. Sandoval as Older Pregnant Parent
Derek Basco as Room Service Waiter
Nicol Paone as E.R. Nurse
Lynne Alana Delaney as Disturbed Restaurant Patron (uncredited)
Katia Kieling as BBQ Guest (uncredited)
Bill Hader as Desi's Store Pickup (uncredited)
Tom Everett as Pete's Doctor
Tatum O'Neal as Realtor
Ryan Adams as Ryan Adams
Ryan Lee as Joseph
Dan Bakkedahl as Dentist
Jessica Lee as Party Guest #1 (uncredited)
Rebekka Johnson as Gyno Nurse
Johnny Pemberton as Room Service Waiter
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Judd Apatow Producer
Clayton Townsend Producer
Barry Mendel Producer
Jon Brion Original Music Composer
Judd Apatow Director
Judd Apatow Screenplay
Gary Archer Prosthetics
Joe Bucaro III Stunt Double
Tom Elliott Stunt Driver
Leslie A. Pope Set Decoration
Allison Jones Casting
Leesa Evans Costume Design
Jefferson Sage Production Design
George H. Anderson Supervising Sound Editor
Marc Fishman Sound Re-Recording Mixer
Joel Kramer Stunt Coordinator
Valeria Migliassi Collins Script Supervisor
Ken McLaughlin Production Sound Mixer
Adam Jenkins Sound Re-Recording Mixer
Cindy Marty Sound Effects Editor
Andrew Max Cahn Art Direction
Paula Pell Executive Producer
Jay Deuby Editor
Barrett J. Leigh Production Supervisor
Dan Bronson Costume Supervisor
Lisa Goldberg Co-Producer
Phedon Papamichael Director of Photography
Brent White Editor
Suzanne Hanover Still Photographer
David Luckenbach Steadicam Operator
David L. Bertman Editor
Jonathan Karp Music Supervisor
David Luckenbach Camera Operator
Erin E. Riegel Art Department Assistant
Debbie Evans Stunt Driver
Lois Yaroshefsky Studio Teacher
Riley Harper Stunts
Tammy Fearing ADR Supervisor
Larry Kemp Dialogue Editor
Linda Arnold Hair Department Head
James Matheny Dialogue Editor
Matt Rebenkoff First Assistant Director
Joel Kramer Second Unit Director
Sean Mannion Property Master
Dick Ziker Stunt Driver
Ed French Makeup Artist
Valli O'Reilly Makeup Artist
Amy Lederman Makeup Artist
Beth O'Rourke Makeup Artist
Viola Rock Makeup Artist
Kimberly Greene Makeup Department Head
Erin Wooldridge Key Makeup Artist
Michael Moore Key Hair Stylist
Tammy Kusian Hairstylist
Donna J. Anderson Hairstylist
Paul Schneider Second Assistant Director
Donald Frazee Special Effects Coordinator
Scott M. Davids Visual Effects Supervisor
Colin Follenweider Stunt Double
Jack Carpenter Stunts
Wally Crowder Stunts
Steve Hart Stunt Driver
Paul M. Lane Stunt Driver
Scott Leva Stunts
Norman Howell Stunts
Jody Millard Stunt Double
Ed McDermott II Stunt Driver
Stephen W. Schriver Stunt Driver
Tierre Turner Stunt Driver
Mark Aaron Wagner Stunt Double
John R. Leonetti Second Unit Director of Photography
Goran Pavicevic Second Unit Director of Photography