As an asteroid nears Earth, a man finds himself alone after his wife leaves in a panic. He decides to take a road trip to reunite with his high school sweetheart. Accompanying him is a neighbor who inadvertently puts a wrench in his plan.
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Steve Carell as Dodge Petersen
Keira Knightley as Penelope "Penny" Lockhart
Connie Britton as Diane
Rob Corddry as Warren
Adam Brody as Owen
Derek Luke as Alan Speck
Martin Sheen as Frank Petersen
Melanie Lynskey as Karen Amalfi
Nancy Carell as Linda Petersen
William Petersen as Trucker
Gillian Jacobs as Waitress / Katie
T.J. Miller as Chipper Host / Darcy
Patton Oswalt as Roache
Bob Stephenson as Officer Wally Johnson
Brad Morris as Radio Announcer (voice)
Mark Moses as Anchorman
Roger Aaron Brown as Alfred
Rob Huebel as Jeremy
Trisha Gorman as Crying Woman
Tonita Castro as Elsa
Leslie Murphy as Amy
Kasey Campbell as Danny
Vince Grant as Man #1 / Chip
Amy Schumer as Woman #1 / Lacey
Marshall Manesh as Indian Man
Aleister as Sorry
Rene Gube as Cell-Mate
Jim O'Heir as Cop #2
Daniel Maurio as Toilet Guy
Matthew Alan Brady as Kissing Couple In Park (uncredited)
Tony Brown as Gay Party Guest (uncredited)
Lauren Crawford as Bikini Girl (uncredited)
Laura Mann as Sarah (uncredited)
Prestin Persson as Bikini Girl (uncredited)
Lauren K. Solomon as Kissing Friendsy's Customer (uncredited)