Intolerance (2000)

The film begins with an Earth space craft stumbling upon a movie floating in the vast nothingness. The film turns out to be from planet Zog and when people see it, they are shocked and angered by the Zogs (or is it 'Zogians' or 'Zogites'?). It seems that they have their genitals where our heads are and vice-versa. To make things really weird, they eat and drink with their genitals and defecate with their faces.

Comedy Science Fiction Animation