Andy moves to New York to work in the fashion industry. Her boss is extremely demanding, cruel and won't let her succeed if she doesn't fit into the high class elegant look of their magazine.
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Meryl Streep as Miranda Priestly
Anne Hathaway as Andy Sachs
Emily Blunt as Emily
Stanley Tucci as Nigel
Simon Baker as Christian Thompson
Adrian Grenier as Nate
Tracie Thoms as Lily
Rich Sommer as Doug
Daniel Sunjata as James Holt
David Marshall Grant as Richard Sachs
James Naughton as Stephen
Tibor Feldman as Irv Ravitz
Rebecca Mader as Jocelyn
Jimena Hoyos as Lucia
Gisele Bündchen as Serena
George C. Wolfe as Paul
John Rothman as Editor
Stephanie Szostak as Jacqueline Follet
Colleen Dengel as Caroline
Suzanne Dengel as Cassidy
Heidi Klum as Heidi Klum
Valentino Garavani as Valentino Garavani
Bridget Hall as Bridget Hall
Ines Rivero as Clacker in Elevator
Alyssa Sutherland as Clacker
Robert Verdi as Fashion Reporter
Paul Keany as St. Regis Butler
David Callegati as Massimo
Rori Cannon as Girl at Party
Stan Newman as John Folger
James Cronin as Ambassador
Eric Seltzer as Roy
Lindsay Brice as PR Woman
Steve Benisty as Fashion Photographer
John Graham as Book Guy
Wells Dixon as Miranda's Driver
Ilona Alexandra as Red Carpet Celebrity (uncredited)
Frank Anello as Security (uncredited)
Alexander Blaise as French Bellhop (uncredited)
Carl Burrows as Businessman (uncredited)
Guy A. Fortt as Security (uncredited)
Alexie Gilmore as Clacker (uncredited)
Toree Hill as Guest (uncredited)
Tim Krueger as Fund Raiser (uncredited)
Hector Lincoln as Hector Lincoln (uncredited)
Nina Lisandrello as Clacker (uncredited)
Zev McAllister as Runway Editor (uncredited)
Matt Murray as Paparazzo (uncredited)
Ingrid Sophie Schram as Clacker (uncredited)
Bobby Shue as Runway Staff (uncredited)
Brandhyze Stanley as Waitress (uncredited)
Jen Taylor as Lou - Dowager (uncredited)
Taylor Treadwell as Miranda's New Assistant (uncredited)
Donatella Versace as Donatella Versace (uncredited)
Lauren Weisberger as The Twins' Nanny (uncredited)
Laura D. Williams as Runway Magazine Model / Party Guest (uncredited)