In an effort to be able to afford expensive treatment for her gravely ill American husband, a retired German entertainer returns to the cabaret as Blonde Venus and catches the eye of a wealthy politician.
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Marlene Dietrich as Helen Faraday, aka Helen Jones
Herbert Marshall as Edward 'Ned' Faraday
Cary Grant as Nick Townsend
Dickie Moore as Johnny Faraday
Gene Morgan as Ben Smith
Rita La Roy as 'Taxi Belle' Hooper
Robert Emmett O'Connor as Dan O'Connor
Sidney Toler as Detective Wilson
Morgan Wallace as Dr. Pierce
Al Bridge as Bouncer (uncredited)
Marcelle Corday as Helen's Maid in France (uncredited)
Cecil Cunningham as Cabaret Manager in Norfolk (uncredited)
Sterling Holloway as Joe, Hiker (uncredited)
Hattie McDaniel as Cora, Helen's Maid in New Orleans (uncredited)
Dennis O'Keefe as (uncredited)
Dewey Robinson as Restaurant Owner (uncredited)
Bess Flowers as (uncredited)
Francis Sayles as Charlie Blaine (uncredited)
Glen Cavender as Ship's Officer (uncredited)
Émile Chautard as Chautard, Cabaret Manager in France (uncredited)
Clifford Dempsey as Judge in New Orleans (uncredited)
Charles Gemora as Helen Faraday in Gorilla Suit (uncredited)
Robert Graves as (uncredited)
Elsa Janssen as Gossiping Tenant (uncredited)
Bessie Lyle as Viola, Hotel Maid in Norfolk (uncredited)
Charles R. Moore as Charlie, the Bartender (uncredited)
Charles Morton as Bob, Hiker (uncredited)
Evelyn Preer as (uncredited)
Gertrude Short as Sally, Receptionist at Talent Agency (uncredited)
Pat Somerset as Henry Johnson (uncredited)
Larry Steers as Hotel Manager in Baltimore (uncredited)
Kent Taylor as Hiker (uncredited)
Jerry Tucker as (uncredited)
Lloyd Whitlock as (uncredited)
James Kilgannon as Landlord (uncredited)
Mary Gordon as Landlady (uncredited)
Harold Berquist as Angry Man in Nightclub (uncredited)