As the railroad builders advance unstoppably through the Arizona desert on their way to the sea, Jill arrives in the small town of Flagstone with the intention of starting a new life.
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Claudia Cardinale as Jill
Henry Fonda as Frank
Jason Robards as 'Cheyenne'
Charles Bronson as 'Harmonica'
Gabriele Ferzetti as Morton
Paolo Stoppa as Sam
Woody Strode as Frank's Gunman
Jack Elam as Frank's Gunman
Keenan Wynn as Sheriff
Frank Wolff as Brett McBain
Lionel Stander as Innkeeper
Frank Braña as Frank's Gunman (uncredited)
Stefano Imparato as Patrick McBain (uncredited)
Claudio Mancini as Hanged Man (uncredited)
Al Mulock as Frank's Gunman (uncredited)
Antonio Palombi as Station Agent (uncredited)
Renato Pinciroli as Bidder (uncredited)
Aldo Sambrell as Cheyenne's Gunman (uncredited)
Conrado San Martín as McBain's Neighbor (uncredited)
Enzo Santaniello as Timmy McBain (uncredited)
Simonetta Santaniello as Maureen McBain (uncredited)
Luana Strode as Cattle Corner Woman (uncredited)
Fabio Testi as Frank's Gunman (uncredited)
Marco Zuanelli as 'Wobbles' (uncredited)
Antonio Molino Rojo as Frank's Gunman (uncredited)
Román Ariznavarreta as Logan (uncredited)
John Frederick as Jim (uncredited)
Aldo Berti as Frank's Gunman (uncredited)
Spartaco Conversi as Frank's Gunman (uncredited)
Saturno Cerra as Frank's Gunman (uncredited)
Paolo Figlia as Frank's Gunman (uncredited)
Dino Mele as Harmonica as a Boy (uncredited)
Simonetta Stefanelli as Maureen McBain (uncredited)
Regina Elena Bisio as Old Woman in the Tavern (uncredited)