Three outlaws on the run discover a dying woman and her baby. They swear to bring the infant to safety across the desert, even at the risk of their own lives.
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John Wayne as Robert Marmaduke Sangster Hightower
Pedro Armendáriz as Pedro 'Pete' Roca Fuerte
Harry Carey, Jr. as William Kearney ('The Abilene Kid')
Ward Bond as Perley 'Buck' Sweet
Mae Marsh as Mrs. Perley Sweet
Mildred Natwick as The Mother
Jane Darwell as Miss Florie
Guy Kibbee as Judge
Dorothy Ford as Ruby Latham
Ben Johnson as Posse man #1
Charles Halton as Oliver Latham
Hank Worden as Deputy Curly
Jack Pennick as Luke
Fred Libby as Deputy
Michael Dugan as Posse Man #2
Don Summers as Posse Man #3
Gertrude Astor as Saloon Girl (uncredited)
Richard Hageman as Saloon Pianist (uncredited)
Nora Bush as Townswoman (uncredited)
Eva Novak as Townswoman (uncredited)
Charles Soldani as Townsman (uncredited)
Ruth Clifford as Woman in Bar (uncredited)
Jack Curtis as Bartender (uncredited)
Harry Tenbrook as Bartender (uncredited)
Tex Driscoll as Barfly (uncredited)
Jack Kenny as Barfly (uncredited)
Jack Mower as Barfly (uncredited)
Francis Ford as Drunk (uncredited)
Cliff Lyons as Guard at Mojave Tanks (uncredited)
Amelia Yelda as Robert William Pedro Hightower (the Baby) (uncredited)
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John Ford Director
Laurence Stallings Screenplay
Frank S. Nugent Screenplay
Merian C. Cooper Producer
John Ford Producer
Richard Hageman Original Music Composer
Jack Murray Editor
James Basevi Art Direction
Winton C. Hoch Director of Photography
Joseph Kish Set Decoration
Don L. Cash Makeup Artist
Anna Malin Hairstylist
Lowell J. Farrell Production Manager
Edward O'Fearna Assistant Director
Wingate Smith Assistant Director
Frank Wesselhoff Painter
Joseph I. Kane Sound
D. Pat Kelley Sound Effects
Jack Caffee Special Effects
Cliff Lyons Stunts
Charles P. Boyle Second Unit Director of Photography