With the help of Pocahontas, Captain John Smith overcomes the treachery of some of his men and resentment of the local Native Americans to establish the colony of Jamestown.
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Anthony Dexter as Capt. John Smith
Jody Lawrance as Pocahontas
Alan Hale Jr. as Fleming
Robert Clarke as Rolfe
Stuart Randall as Opechanco
James Seay as Wingfield
Philip Van Zandt as Davis
Shepard Menken as Nantaquas
Douglass Dumbrille as Powhatan (as Douglas Dumbrille)
Anthony Eustrel as King James
Henry Rowland as Turnbull
Eric Colmar as Kemp
Joan Dixon as Indian Maiden (uncredited)
Francesca De Scaffa as Powhatan Maiden (uncredited)
Beulah Archuletta as Powhatan Woman (uncredited)
Charles Soldani as Powhatan tribesman (uncredited)
Tony Urchel as Powhatan tribesman (uncredited)
William Cottrell as Macklin (uncredited)
Billy Wilkerson as Sub-Chief (uncredited)
John Maxwell as Ship's Doctor (uncredited)
Jack Kenny as Settler who Discovers Gold (uncredited)